Professor; Department Chair – Behavioral and Cognitive Neuroscience
Department of Psychology, Brain and Mind Institute, Western University
My research interests relate to the organization of episodic memory in the human brain. As part of the discipline of cognitive neuroscience, my research addresses the relationship between the cognitive and neural processes that allow humans to remember their past. It builds upon diverse methodological approaches, such as the investigation of memory impairments in neurological patients, cognitive experiments in healthy individuals, the examination of brain activity with functional neuroimaging techniques (fMRI), and brain stimulation with transcranial magnetic stimulation (TMS). Some of the specific questions addressed concern how memory systems interact with the visual system when we recognize something we say earlier, whether different parts of the brian support memory for different types of information, and how memory processes contribute to the detection of novelty in the environment.
Our lab’s general research interests pertains to the functional and neuroanatomical organization of episodic memory in the human brain. As part of the discipline of cognitive neuroscience, this research addresses the relationship between the cognitive and neural processes that allow humans to remember the past. Our research builds upon diverse methodological approaches: the investigation of memory impairments in neurological patients, cognitive experiments in healthy individuals, the examination of brain activity with functional neuroimaging techniques (fMRI), and brain stimulation with transcranial magnetic stimulation (TMS). Questions addressed by our lab include how memory systems interact with the visual system, whether different parts of the brain support memory for different types of information, and how memory processes contribute to the detection of novelty in the environment.
O’Neil, E.B., Cate, A.D., & Köhler S. (2009). Perirhinal cortex contributes to accuracy in recognition memory and perceptual discriminations. Journal of Neuroscience, 29, 8329–8334.
Poppenk, J., Walia, G. , Joanisse, M.F., Klein, D., McIntosh, A.R., & Köhler S. (2008). Why is the meaning of a sentence better remembered than its form? An fMRI study on the role of novelty-encoding processes. Hippocampus, 18, 909-918.
Bowles B., Crupi C., Mirsattari S.M., Pigott S.E., Parrent A.G., Pruessner J.C., Yonelinas A.P., Köhler, S. (2007) Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus. Proceedings of the National Academy of Sciences USA, 104, 16382-16387.
Danckert, S.L., Gati, J., Menon, R.S., & Köhler, S. (2007). Perirhinal and hippocampal contributions to visual recognition memory can be distinguished from those of occipito-temporal structures based on conscious awareness of prior occurrence. Hippocampus, 17, 1081-1092.
Robertson, E.K. & Köhler, S. (2007). Insights from child development on the relationship between episodic and semantic memory. Neuropsychologia, 45, 3178-3189.
Cate, A.D. & Köhler, S. (2006). The missing whole in perceptual models of perirhinal cortex. Trends in Cognitive Sciences, 10, 396-397.
Ganel, T., Gonzalez, C.L.R., Valyear, K.F., Culham, J.C., Goodale, M.A., & Köhler, S. (2006). The relationship between fMRI adaptation and repetition priming. Neuroimage, 32, 1432-1440.
Köhler, S., Danckert S., Gati J. S., & Menon R.S. (2005) Novelty responses to relational and non-relational information in the hippocampus and the parahippocampal region: A comparison based on event-related fMRI. Hippocampus, 15, 763-774.
Rosenbaum, R.S., Köhler, S., Schacter, D.L., Moscovitch, M., Westmacott, R., Black, S.E., Gao, F., & Tulving, E. (2005). The Case of K.C.: Contributions of a memory-impaired person to memory theory. Neuropsychologia, 43, 989-1021.
Köhler S., Paus, T., Buckner, R.L. & Milner, B. (2004). Effects of left inferior prefrontal stimulation on episodic memory formation: A two-stage fMRI-rTMS study. Journal of Cognitive Neuroscience, 16, 178-188.
Köhler S., Crane J., & Milner B. (2002). Differential contributions of the parahippocampal place area and the anterior hippocampus to human memory for scenes. Hippocampus, 12, 718-723.
Köhler S, Moscovitch M, & Melo B. (2001). Episodic memory for object location versus episodic memory for object identity: do they rely on distinct encoding processes? Memory & Cognition, 29, 948-959.
Rosenbaum R.S., Priselac S, Köhler S., Black S.E., Gao F., Nadel L., & Moscovitch M. (2000). Remote spatial memory in an amnesic person with extensive bilateral hippocampal lesions. Nature Neuroscience, 3, 1044-1048.
Köhler, S., McIntosh, A.R., Moscovitch, M., & Winocur, G. (1998). Functional interactions between the medial temporal lobes and posterior neocortex related to episodic memory retrieval. Cerebral Cortex, 8, 451-461.
Köhler, S., Black, S.E., Sinden, M., Szekely, C., Kidron, D., Parker, J.L., Foster, J.K., Moscovitch, M., Winocur, G., Szalai, J.P., & Bronskill, M.J. (1998). Memory impairments associated with hippocampal versus parahippocampal-gyrus atrophy: An MR volumetry study in Alzheimer’s disease. Neuropsychologia, 36, 901-914.
Köhler, S., Moscovitch, M., Winocur, G., Houle, S., & McIntosh, A.R. (1998). Networks of domain-specific and general regions involved in episodic memory for spatial location and object identity. Neuropsychologia, 36, 129-142.
Köhler, S. & Moscovitch, M. (1997). Unconscious visual processing in neuropsychological syndromes: A survey of the literature and evaluation of models of consciousness. In M.D. Rugg (Ed.), Cognitive Neuroscience (pp. 305-373). Cambridge, MA: MIT Press.
Psychology 3224A/B – Neuropsychology and Cognitive Neuroscience
Psychology 3238F/G – Memory
Psychology 9222 – Cognitive Neuroscience of Memory