Ethical and Policy Issues in Cluster Randomized Trials

doctor in hospital room

The gap between medical evidence and medical practice is one of the most important challenges for the health of Canadians. The cluster randomized trial (CRT) is the major methodological tool in use in the development of new interventions to bridge the gap between evidence and practice. This project brings together clinical trialists, biostatisticians, and philosophers to address ethical and policy obstacles to the conduct of CRTs. A major outcome is the development of international ethics guidelines for CRTs.


  • Monica Taljaard (Nominated Principal Investigator; Ottawa Hospital Research Institute)

  • Jeremy Grimshaw (Ottawa Hospital Research Institute)

  • Charles Weijer (Rotman Institute of Philosophy, Western University)

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